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5th Scientific
Meeting of the European Network for the Study of Adrenal Tumours
(ENS@T)
Friday, November 03:
13.00 - Get together and Introduction
Session I (13:30 - 15:15) - Update
on current ENS@T projects from the ACC and NAPACA Working
group (chaired by B. Allolio)
13:30 - TIS11 family proteins and
the control of mRNA stability in the adrenal cortex
N. Cherradi, Grenoble
13:45 - BMP dependent effects on
adrenal tumorigenesis
I. Johnsen, Freiburg/Munich
14:00 - Potential role of type I
interferons in adrenocortical carcinoma growth
L. Hofland, Rotterdam
14:15 - Phenotypical characterization
of the NCI side population
F. Beuschlein / U. Lichtenauer, Munich/Freiburg
14:30 - Uppsala experience of the
role of PET-scanning in management of ACC
B. Skogseid, Uppsala
14:45 - Prognostic markers of adrenal
cortical tumors: a molecular approach and The Carney complex
cohort: follow-up
J. Bertherat, Paris (from Session IV, Proposals)
15:00 Urinary steroid profiling via
GC/MS in ACC - first results of EURINE ACC
W. Arlt, Birmingham
Coffee break (15:15-15:30)
Session II (15:30-17:15): Update on current
ENS@T projects from the APA Working group (chaired by F. Mantero)
15:30 - Prospective comparison of
the captopril and the saline infusion test for excluding primary
aldosteronism due to aldosterone-producing adenoma: results
of the PAPY Study and proposal for collaborative studies
G.P. Rossi and F. Mantero, Padua
15:45 - Prediction of outcome in
168 patients with PA having undergone adrenalectomy
E. Letavernier, Paris
16:00 - Introduction of the German
Conn Registry
M. Quinkler, Berlin
16:15 - Role of endothelial cells
in modulation of aldosterone release
I. Ansurudeen, Dresden
16:30 - Quantitative expression of
urotensin-II and urotensin-II receptor in the normal human
adrenal gland, aldosterone-producing adenomas and pheochromocytoma.
L. Giuliani, Padua
16:40 - G-protein coupled receptor
expression in APA - microarray and RT-PCR results from Padua
and Paris
B. Mariniello Padua and C. Zennaro, Paris
17:00 Aberrant receptor expression
in PA - clinical characterization
O. Zwermann, Munich
Coffee break (17:15-17:30)
Session III (17:30-19:15): Update on current ENS@T projects
from the Pheo Working group (chaired by P.-F. Plouin)
17:30 - Hereditary PGL in France:
the PGL.NET cohort
A. P. Gimenez-Roqueplo, Paris
17:45 - Novel VHL mutations with
unusual clinical presentation
T. Ercolino, Florence
18:00 - Novel markers and targets
for the prognosis and treatment of malignant pheochromocytomas
Y. Anouar, Rouen
18:15 - SDHB gene mutations predict
survival in patients with malignant PH and PGL
L. Amar, Paris
18:30 - Very low penetrance of SDHB
mutation in three Italian families with a large number of
carriers
G. Opocher, Padua
18:45 - Detection of large rearrangements
in the PH/PGL genes using QMPSF
N. Burnichon, Paris
19:00 - A VHL intronic sequence variant
associated with pheochromocytoma
F. Schiavi, Padua
Dinner (20:00 -23:00)
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Saturday, November 04:
Morning Session: Update on current "ENS@T
projects" (09h00 - 12h00)
Session IV (09:00-11:00): Proposal for
future ENS@T projects (chaired by M. Reincke)
09:00 - Special topic: How to set
up a genetic screen for patients with sporadic PA
T. Meitinger, Munich
09:25 - Evaluation of adrenal masses:
the 18-FDG approach
X. Bertagna, Paris (from Session I, ACC and NAPACA)
09:40 - The metabolic syndrome in
patients with incidentally detected adrenal adenomas: evaluation
of the outcome of adrenalectomy compared to conservative management
M. Terzolo, Torino
09:55 - Quality control in laboratory
assessment of aldosterone and renin in biological fluids
M. Bidlingmaier, Munich
10:10 - Genetic regulation of aldosterone:
interactions between CYP11B1 and CYP11B2
J. Connell, Glasgow
10:25 - Further implementation of
a European database of Pheo/PGL gene mutations and polymorphisms
A. P. Gimenez-Roqueplo, Paris
10:40 - Multi-targeted tyrosin-kinase
inhibitor - new options for refractory ACC patients - discussion
of two potential phase II trials
A. Berruti, Torino and M. Fassnacht, Würzburg
Coffee break (11:00) and End of Session
ENS@T Steering committee meeting (11:00
- 14:00)
14:00 - End of Meeting
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